Webinar: Developments with the Threshold of Toxicological Concern (TTC)

Smithers Pira provides an overview of the Threshold of Toxicological Concern, and the implications it has.

Download this recorded webinar now at the bottom of the page.

Webinar first ran: Wednesday 28 November 2012. 


Improved analytical methods mean that increasing numbers of substances present at low and very low concentrations in food are now detectable. However, for many substances there are little or no toxicological data available. There is an increased need to assess the potential health significance of these previously undectable trace substannces and it is not always possible to generate toxicological data on every single substance found in the diet. 

The Threshold of Toxicological Concern (TTC) approach is a science-based tool that can be used to screen chemicals. The TTC approach has been developed to quantitatively assess the risk of low-level substances in the diet. It can be used for an initial assessment of a substance to determine whether a comprehensive risk assessment is required*. 

The discussion focuses on:

  • What is the Threshold of Toxicological Concern (TTC)?
  • What does it do?
  • ESFA and the TTC
  • How the TTC makes it easier to deal with unintentional migrants

*quoted from EFSA

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